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FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.

FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.

June 15, 2025 Category: Blog

Friedreich ataxia is caused by an expanded GAA triplet-repeat sequence in intron 1 of the FXN gene that results in epigenetic silencing of the FXN promoter.This silencing mechanism is seen in patient-derived lymphoblastoid cells but NEFF N70 T27CS59S0 Gas Hob - Black it remains unknown if it is a widespread phenomenon affecting multiple cell types

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Classification of Subtypes of Apert Syndrome, Based on the Type of Vault Suture Synostosis

June 15, 2025 Category: Blog

Background:.Apert syndrome patients are different in clinical pathology, including obstructive sleep apnea, cleft palate, and mental deficiency.These functional deficiencies may be due to anatomic deformities, which may be caused by different forms of associated suture fusion.Therefore, a classification system of Apert syndrome Apparel based on the

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In vitro response of dental pulp stem cells in 3D scaffolds: A regenerative bone material

June 15, 2025 Category: Blog

Three-dimensional-porous scaffolds bearing of bone graft substitutes play a critical role in both cell targeting and transplantation strategies.These scaffolds provide surfaces that facilitate the response of stem cells related to attachment, survival, migration, proliferation, and differentiation.Objective: The aim of this study was to evaluate th

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